BREAKTHROUGH DISCOVERY IN NUTRITIONAL IMMUNOLOGY:
Diindolylmethane (DIM) is a Powerful Natural Immune System Booster
At the University of California at Berkeley, the Chairman of the Nutritional Sciences Department and the Director of the National Institutes of Health Cancer Research Program were studying the biological properties of Diindolylmethane (DIM), a naturally occurring compound found in Brassica vegetables (broccoli, cauliflower, cabbage, kale, brussels sprouts), when they made a remarkable discovery: DIM is a potent activator of the immune response system–the most powerful natural immune system booster in the field of nutritional science based on its unique molecular biology and comprehensive enhancement of the entire immune response system.
Shortly after publishing this seminal discovery, which sent shockwaves in the emerging field of nutritional immunology, the scientists at Berkeley co-founded Berkeley BioSciences, Inc. to research and develop nutritional products and therapeutics leveraging this important finding. The Berkeley Immune Support Formula is the first product of Berkeley BioSciences–a first-in-class nutritional supplement designed to enhance the immune system and help raise funds for nature-based biomedical research. The nutritional immune system booster combines multiple nutrients for maximum effectiveness: Diindolylmethane (DIM), Sulforaphane, Selenium, Zinc, Citrus Bioflavonoids, Lycopene, Lutein, Zeaxanthin, and Vitamin D3.
Formulated by the original scientific discoverers of DIM at Berkeley, who together have published more scientific papers on Diindolylmethane than any other scientific team in the world, the Berkeley Formula is regarded by doctors and nutritional scientists worldwide as the most effective bioavailable DIM supplement and immune system booster in the market today. It is the DIM supplement of choice by doctors and nutritional scientists who are actively conducting research on Diindolylmethane (DIM) in conjunction with the other important nutrients found within this unique and proprietary formulation. It is also the supplement of choice for immunologists worldwide conducting research on nutritional methods to boost the immune system effectively.
Engineered by doctors and nutritional scientists for doctors, biomedical investigators and health-conscious consumers, it is the preferred DIM supplement and immune system booster used within prestigious clinical practices and important clinical studies. If you have any technical questions about this Diindolylmethane (DIM) immune system booster and how it nutritionally enhances the immune system, please call our customer service number and we will be happy to answer any questions that you may have about the Berkeley Formula and any of the nutrients within it.
Immune System Booster and Sports Nutrition Leader
Intense endurance sports, stress from work or school, environmental pollution, lack of sleep, and the aging process all take a toll on the immune system. Revive your immune system today with an immune system booster so powerful and clinically effective that physicians and biomedical investigators worldwide have made it a part of their daily nutritional wellness program.
Competitive endurance sports athletes are advised to take this DIM supplement immediately after their workouts or competitive matches to help counter the impact of intense sports activity on the immune system.
Bioavailable and Bioactive Nutrient Delivery System
Scientifically validated and inspired by the Mediterranean diet, the Berkeley Formula is the first immune system booster in the market to combine the phytonutrients found in broccoli, spinach and tomatoes with bioflavonoids found in whole citrus fruits (including citrus peel) for a comprehensive nutritional immune support formula that resembles the benefits one gets when one consumes a large salad bowl of these vegetables prepared with fresh citrus juice and chopped citrus peel on a daily basis. Another component of our Mediterranean-inspired immune system booster has to do with the sunshine vitamin, namely, Vitamin D3, which recently has been shown to play an important role in enhancing the immune system.
The Berkeley DIM Immune Complex is engineered for maximum bioavailability and our product is the first immune system booster in the market to deliver a bioactive quantity of DIM to consumers. The Sulforaphane in the Berkeley Immune Support Formula comes from Myrosinated Sulforaphane Glucosinolate, a proprietary manufacturing process developed exclusively by our scientists that delivers the most bioavailable and bioactive formulation of Sulforaphane in the market today.
Worldclass Science and Technology
The Co-Founders and Scientific Advisory Board members of Berkeley BioSciences are internationally renowned scientists in the fields of nutrition, oncology and immunology:
Proceeds from the Berkeley Immune Support Formula support biomedical research.
Thank you for your support.
DIM Supplement Promotion of Breast Health
Our scientific team was the first in the world to discover through a human clinical trial that DIM, in addition to its immune enhancing properties, also promotes healthy estrogen metabolism, a biological process that has been clinically shown to promote breast health in women.1, 2, 3, 4
You’ve probably come across news articles and blog posts on the internet claiming that DIM “balances hormones” in the body. That statement is actually scientifically incorrect. What we established in our human clinical trial that we published is that DIM helps to promote healthy estrogen metabolism.
You see, when estrogen is metabolized prior to its excretion by the body, there are two metabolic pathways that it takes. One of those pathways produces an intermediary compound that is a more powerful hormone than estrogen itself, namely, 16-alpha hydroxyestrone (16alpha-OHE1), and the production of this intermediary compound has been associated with a variety of health issues in women, especially breast health issues. There is a secondary metabolic pathway that produces a neutral compound that has little hormonal activity, namely, 2-hydroxyestrone (2-OHE1). The presence of this secondary intermediary compound in the metabolism of estrogen has been associated with the promotion of breast health.5
Epidemiological studies have shown that women who genetically have a propensity to metabolize estrogen through the second pathway enjoy significant health benefits.5 One of the goals in the field of clinical nutrition has been to study nutritional methods through which this pathway can be safely shifted toward the secondary metabolic pathway.
When we discovered in our human clinical trial at Berkeley that DIM nutritionally shifts the metabolism of estrogen toward this beneficial secondary metabolic pathway, our study caught the attention of the scientific community worldwide and it led to a significant interest in the biomedical community to do more research on this remarkable compound from broccoli.
It has been over three decades now since we initially started studying DIM at Berkeley and we’re glad to see how the important biology that this compound potentiates has been explored and elucidated in hundreds of studies by our colleagues worldwide.
This is why the Berkeley Formula is recommended by doctors and nutritional scientists as both an effective immune system booster and a DIM supplement that supports breast health. Our team conducted that first and original study that led to a lot of interest in Diindolylmethane (DIM) by women’s health specialists and health-conscious women worldwide.
DIM Supplement Promotion of Prostate Health
Just as our studies on DIM in the promotion of healthy estrogen metabolism caused a lot of women worldwide to start looking into incorporating DIM into their daily nutritional wellness programs, our studies on how DIM promotes prostate health at the cellular level were also noted by the press worldwide and made DIM a very popular supplement among health-conscious men.6, 7, 8, 9
Our studies of DIM and its promotion of prostate health caused an additional wave of interest in the biomedical community to study the effect of Diindolylmethane (DIM) in the promotion of healthy aging in men worldwide. This is one of the reasons why prostate health specialists often recommend our product as both an immune system booster and a DIM supplement to men interested in maintaining a healthy prostate gland.
We hope that you enjoy our product that is the result of over 30 years of scientific research. We look forward to continuing our research in clinical nutrition to promote healthy aging in men and women worldwide.
If you have any technical questions regarding our product, please feel free to reach out to our customer service representatives. Our representatives are trained to answer most questions about our product and why it is the DIM supplement of choice by doctors and nutritional scientists worldwide. For extensive technical questions about our product or Diindolylmethane (DIM) that require a molecular biologist to answer your questions, we also have expert biologists on staff who are a part of our scientific team that can answer your technical DIM supplement questions.
Berkeley Formula Nutrikinetics
Our product goes beyond just providing DIM in a bioavailable manner. Our goal in the development of this product has been to pay meticulous attention to the nutrikinetics of the nutrients that we provide together. The C-maxes of each of the nutrients has been designed to maximally overlap with each other to maximize their combined effect on the immune system and other organ systems in the body. C-max in the field of nutrition refers to the maximum concentration of a particular nutrient within the bloodstream after ingestion. When two or more nutrients are noted to work well together to achieve a desired biological result, the overlapping of their C-max curves helps to deliver maximum clinical efficacy to end consumers. The dosages, the bioavailabilities and the kinetics of absorption of each nutrient has been engineered to achieve this maximum combined impact within the Berkeley Formula. We’re one of the few dietary supplements in the industry that has been engineered by senior nutritional scientists and molecular biologists with clinical efficacy being our number one priority.
1. Journal of Nutritional Biochemistry 2008 May; 19(5): 336–344. Xue L, Pestka J, Maoxiang L, Firestone GL, Bjeldanes LF. Department of Nutritional Sciences and Toxicology, University of California at Berkeley, 119 Morgan Hall, Berkeley, CA 94720-3104, USA
2. Molecular Pharmacology 2006 Feb;69(2):430-9. Riby JE, Xue L, Chatterji U, Bjeldanes EL, Firestone GL, Bjeldanes LF. Department of Nutritional Sciences and Toxicology, University of California at Berkeley, 119 Morgan Hall, Berkeley, CA 94720-3104, USA
3. Oncogene 2005 Mar 31;24(14):2343-53. Xue L, Firestone GL, Bjeldanes LF. Department of Nutritional Sciences and Toxicology, University of California at Berkeley, 119 Morgan Hall, Berkeley, CA 94720-3104, USA
4. Journal of Nutrition and Cancer 2004;50(2):161-7. Dalessandri KM, Firestone GL, Fitch MD, Bradlow HL, Bjeldanes LF. Department of Molecular and Cell Biology, University of California, Berkeley, 94720-3200, USA
5. Epidemiology 2000 Nov;11(6):635-40. Muti P, Bradlow HL, Micheli A, Krogh V, Freudenheim JL, Schunemann HJ, Stanulla M, Yang J, Sepkovic DW, Trevisan M, Berrino F. Department of Social and Preventive Medicine, University at Buffalo, State University of New York at Buffalo, Buffalo, NY, USA, Epidemiology Division of the National Cancer Intitute (Istituto Nazionale Tumori), Milan, Italy, Department of Pediatric Hematology and Oncology, Medical School of Hannover, Hannover, Germany
6. Biochemical Pharmacology 2009 Sep 1;78(5):469-76. Vivar OI, Lin CL, Firestone GL, Bjeldanes LF. Department of Nutritional Sciences and Toxicology, 119 Morgan Hall, University of California, Berkeley, CA 94720, USA
7. Carcinogenesis 2005 Nov;26(11):1896-904. Hsu JC, Zhang J, Dev A, Wing A, Bjeldanes LF, Firestone GL. Department of Molecular and Cell Biology, University of California at Berkeley, CA 94720, USA
8. Journal of Biological Chemistry 2003 Jun 6;278(23):21136-45. Le HT, Schaldach CM, Firestone GL, Bjeldanes LF. Department of Nutritional Sciences and Toxicology, University of California, Berkeley, California 94720-3104, USA
9. Please visit our extensive references section at the end of our Science Page listing scientific articles on Diindolylmethane, Sulforaphane, Selenium and the other nutrients within the Berkeley Formula.
Brassica Microgreens Spring Salad. Our scientific team’s favorite menu item at the UC Berkeley Faculty Club.
Brassica Microgreens Spring Salad.
Our scientific team’s favorite menu item at the UC Berkeley Faculty Club.
Alex Amini, M.D.
Infectious Disease Specialist
Powerful Nutritional Immune Booster
Bioavailable Nutrient Delivery System
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Immune, Breast, Prostate & Vision Health
The bright orange color of the Berkeley Formula capsules comes from a rich mixture of Carotenoids within the product: Lutein, Lycopene, Zeaxanthin and Marigold Flower Extract. Most of the other purified ingredients within the product are either white or off-white in color and therefore do not affect the product’s color very much. Our capsules are transparent so that users can see what is inside.